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BODIPY Peptide Labeling by Late-Stage C(sp3 )-H Activation.

Wei WangMélanie M LorionOscar MartinazzoliHarry L Anderson
Published in: Angewandte Chemie (International ed. in English) (2018)
Late-stage BODIPY diversification of structurally complex amino acids and peptides was accomplished by racemization-free palladium-catalyzed C(sp3 )-H activation. Transformative fluorescence modification proved viable by triazole-assisted C(sp3 )-H arylation in a chemo- and site-selective fashion, providing modular access to novel BODIPY peptide sensors.
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