Mice lacking melatonin MT2 receptors exhibit attentional deficits, anxiety and enhanced social interaction.

David M ThomsonEmma J MitchellRebecca L OpenshawJudith A PrattBrian J Morris

Published in: Journal of psychopharmacology (Oxford, England) (2021)

The results confirm that the MT2 receptor plays a role in cognition and also modulates anxiety and social interactions. These data provide new insights into the functions of endogenous melatonin and will inform future drug development strategies focussed on the MT2 receptor.

Keyphrases

healthcare
mental health
sleep quality
traumatic brain injury
working memory
current status
big data
high fat diet induced
metabolic syndrome
binding protein
machine learning
multiple sclerosis
depressive symptoms
physical activity
data analysis