Hypoxia is not the primary mechanism contributing to exercise-induced proteinuria.
Kelsley E JoyceJohn DelamereSusie BradwellStephen David MyersKimberly AshdownCarla RueSamuel Je LucasOwen D ThomasAmy FountainMark EdsellFiona MyersWill MaleinChris ImrayAlex ClarkeChrisopher T LewisCharles NewmanBrian JohnsonPatrick CadiganAlexander WrightArthur R BradwellPublished in: BMJ open sport & exercise medicine (2020)
Profound systemic hypoxia imposed by altitude does not result in greater post-exercise proteinuria than sea level. Losartan and acetazolamide may attenuate post-exercise proteinuria, however further research is warranted.