The X-Linked Helicase DDX3X Is Required for Lymphoid Differentiation and MYC-Driven Lymphomagenesis.

Marion LacroixHugues BeaucheminJennifer FraszczakJulie RossPeiman ShooshtarizadehRiyan ChenTarik Möröy

Published in: Cancer research (2022)

The sex-dependent effects of DDX3X deficiency in malignant transformation of B cells and the compensatory role of DDX3Y support inhibition of DDX3 as a treatment strategy for MYC-driven B-cell lymphoma.

Keyphrases

transcription factor
diffuse large b cell lymphoma
combination therapy