Login / Signup

The X-Linked Helicase DDX3X Is Required for Lymphoid Differentiation and MYC-Driven Lymphomagenesis.

Marion LacroixHugues BeaucheminJennifer FraszczakJulie RossPeiman ShooshtarizadehRiyan ChenTarik Möröy
Published in: Cancer research (2022)
The sex-dependent effects of DDX3X deficiency in malignant transformation of B cells and the compensatory role of DDX3Y support inhibition of DDX3 as a treatment strategy for MYC-driven B-cell lymphoma.
Keyphrases
  • transcription factor
  • diffuse large b cell lymphoma
  • combination therapy