Hyperpolarized 129 Xe imaging of embryonic stem cell-derived alveolar-like macrophages in rat lungs: proof-of-concept study using superparamagnetic iron oxide nanoparticles.

Vlora RiberdyMichael LitvackElaine StirratMarcus J CouchMartin PostGiles E Santyr

Published in: Magnetic resonance in medicine (2019)

Hyperpolarized 129 Xe MRI can detect the presence of SPION-labeled ALMs in the airways 1 h after instillation. This approach is promising for targeting and tracking of stem cells for the treatment of lung disease.

Keyphrases

iron oxide nanoparticles
stem cells
magnetic resonance imaging
high resolution
cystic fibrosis
oxidative stress
cancer therapy
pet imaging
computed tomography
magnetic resonance
cell therapy
combination therapy
diffusion weighted imaging
replacement therapy