Efficacy and safety of inhaled nitric oxide administered during cardiopulmonary bypass for pediatric cardiac surgery: a systematic review and meta-analysis.
Walaa ElnaiemAbdulhay Mohamed ElnourAbubaker E A KokoMaysa MadanyLina HemmedaPublished in: Annals of medicine and surgery (2012) (2023)
NO administered as part of the CPB circuit during cardiac surgeries is efficacious in terms of reducing ventilation time, postoperative IL-6, and TNF-α levels compared to control, with a comparable safety profile.