A thalamic circuit facilitates stress susceptibility via melanocortin 4 receptor-mediated activation of nucleus accumbens shell.
Qiao DengShao-Qi ZhangPing-Fen YangWan-Ting DongJia-Lin WangJian-Guo ChenFang WangLi-Hong LongPublished in: CNS neuroscience & therapeutics (2022)
Our results make a strong case for harnessing a thalamic circuit to reorganize excitatory synaptic transmission in relieving stress susceptibility and provide insights gained on metabolic underpinnings of protection against stress-induced depressive-like behavior.