Sex Affects Regional Variations in Subcutaneous Adipose Tissue T Cells but not Macrophages in Adults with Obesity.
Jessica MurphyKerri Z DelaneyVi DamBjorn T TamNatalie KhorMichael A TsoukasJosé A MoraisSylvia SantosaPublished in: Obesity (Silver Spring, Md.) (2020)
Results showed that T-cell populations vary by SAT region in females but not males. Both sexes, however, have proportionately more proinflammatory macrophages in upper-body than in lower-body SAT. It remains to be seen how these unique immune cell profiles in males and females with obesity contribute to adipose tissue inflammation and metabolic disease risk.