Effects of Apatinib on the "Stemness" of Non-Small-Cell Lung Cancer Cells In Vivo and Its Related Mechanisms.

Bin YangYan WangZhuoying ChenYi-Ming FengLiang-Liang Shi

Published in: Canadian respiratory journal (2020)

Apatinib suppressed the growth of non-small-cell lung cancer cells by repressing the stemness of lung cancer through the inhibition of the Hedgehog, Hippo, and Wnt signaling pathways.

Keyphrases

stem cells
single cell
epithelial mesenchymal transition
cell therapy
mesenchymal stem cells
oxidative stress
pi k akt