Clinical impact of tumour burden on the efficacy of PD-1/PD-L1 inhibitors plus chemotherapy in non-small-cell lung cancer.
Taichi MiyawakiHirotsugu KenmotsuKosei DoshitaHiroaki KodamaNaoya NishiokaYuko IidaEriko MiyawakiNobuaki MamesayaHaruki KobayashiShota OmoriRyo KoKazushige WakudaAkira OnoTateaki NaitoHaruyasu MurakamiKeita MoriHideyuki HaradaMasahiro EndoKazuhisa TakahashiToshiaki TakahashiPublished in: Cancer medicine (2022)
Our findings demonstrated that a high tumour burden negatively impacts the efficacy of ICI + Chemo in patients with advanced NSCLC.