A novel mice model of acute flares in osteoarthritis elicited by intra-articular injection of cultured mast cells.

Junpei DanMasashi IzumiHiroko HabuchiOsami HabuchiShogo TakayaYusuke KasaiRyuzo HayashiKoji AsoTakahiro UshidaMasahiko Ikeuchi

Published in: Journal of experimental orthopaedics (2021)

Our novel model possibly mimics OA flare conditions, which may open a new strategy of disease-modifying treatment for OA, focused on controlling the multiple functions of mast cells.

Keyphrases

knee osteoarthritis
rheumatoid arthritis
minimally invasive
endothelial cells
respiratory failure
type diabetes
drug induced
intensive care unit
skeletal muscle
adipose tissue
combination therapy