Early-stage multi-cancer detection using an extracellular vesicle protein-based blood test.
Juan Pablo HinestrosaRazelle KurzrockJean M LewisNicholas J SchorkGregor SchroederAshish M KamatAndrew M LowyRamez N EskanderOrlando PerreraDavid SearsonKiarash RastegarJake R HughesVictor OrtizIryna ClarkHeath I BalcerLarry ArakelyanRobert TurnerPaul R BillingsMark J AdlerScott M LippmanRajaram KrishnanPublished in: Communications medicine (2022)
This work demonstrates that an EV-based, multi-cancer test has potential clinical value for early cancer detection and warrants future expanded studies involving prospective cohorts with multi-year follow-up.