Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length.
Klara SputovaJames C GarbeFanny A PelissierEric ChangMartha R StampferMark A LaBarge
Published in: Genome integrity (2013)
Telomere shortening did not correlate with the chronological ages of HMEC strains, whereas decreased telomerase activity correlated with age and with lineage distribution phenotypes characteristic of aging.