Diagnostic performance of pupil perimetry in detecting hemianopia under standard and virtual reality viewing conditions.

Overall, these results can be summarized as follows: (1) the comparison of pupil response amplitudes between intact versus damaged regions per patient indicate that gcFPP allows for cleaner imaging of intact versus damaged visual field regions than VRgcFPP, (2) the comparisons of average differences in intact versus damaged amplitudes between patients and controls demonstrate high diagnostic performance of both gcFPP and VRgcFPP, and (3) the test-retest reliabilities confirm that both gcFPP and VRgcFPP reliably and consistently measure defects in homonymous hemianopia. KEY  MESSAGES: What is known Standard automated perimetry is the current gold standard for visual field examination, but not always suited for the evaluation of the VF in neurologically impaired patients. Pupil perimetry consists of the measurement of pupillary responses to light stimuli as a measure of visual sensitivity. What is new This study reports the highest diagnostic accuracy of pupil perimetry so far in patients with homonymous hemianopia. Gaze-contingent flicker pupil perimetry reliably and consistently measures defects in homonymous hemianopia under standard and virtual reality viewing conditions.