Combining a β3 adrenergic receptor agonist with alpha-lipoic acid reduces inflammation in male mice with diet-induced obesity.

Zahraa Abdul SaterCheryl CeroAnne E PierceHannah J LeaHoussein Abdul SaterKenneth Y ZhuNaili LiuYinyan MaOksana GavrilovaAaron M Cypess

Published in: Obesity (Silver Spring, Md.) (2021)

Chronic treatment with ALA and a β3-AR agonist reduces DIO-induced inflammation. AT immune modulation could be a therapeutic target in patients with obesity.

Keyphrases

insulin resistance
oxidative stress
metabolic syndrome
weight loss
high fat diet induced
type diabetes
diabetic rats
weight gain
high glucose
drug induced
adipose tissue
body mass index
combination therapy
endothelial cells
replacement therapy