Clinical correlates of obstructive sleep apnoea in idiopathic normal pressure hydrocephalus.

Regalbuto SimoneZangaglia RobertaValentino Francesca Massimiliano TodiscoPacchetti ClaudioCotta Ramusino MatteoMazzacane FedericoPicascia MartaArceri SebastianoMalomo GaetanoCapriglia ElenaSpelta LauraRubino AnnalisaPisani AntonioTerzaghi Michele

Published in: European journal of neurology (2024)

Obstructive sleep apnoea is highly prevalent in iNPH patients, particularly at moderate to severe levels. OSA is associated with worse motor and cognitive performance in iNPH. The CSF neurodegeneration biomarker profile observed in OSA+ iNPH patients may reflect OSA-induced impairment of cerebral fluid dynamics.

Keyphrases

end stage renal disease
obstructive sleep apnea
positive airway pressure
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
subarachnoid hemorrhage
peritoneal dialysis
physical activity
patient reported outcomes
early onset
oxidative stress
patient reported
diabetic rats