Noninvasive Diagnosis of PLA2R-Associated Membranous Nephropathy: A Validation Study.
Shane A BobartHeedeok HanShahrzad TehranianAn S De VrieseJuan Carlos Leon RomanSanjeev SethiLadan ZandCristina Andrades GomezCallen D GiesenMaria José SolerAndrew S BombackFernando C FervenzaPublished in: Clinical journal of the American Society of Nephrology : CJASN (2021)
In patients with preserved eGFR and absence of associated conditions or diabetes, a positive anti-phospholipase A2 receptor test by either ELISA >20 RU/ml or a positive immunofluorescence assay confirms the diagnosis of membranous nephropathy, precluding the requirement for a kidney biopsy.