Validation of Core Ingredients and Molecular Mechanism of Cinobufotalin Injection Against Liver Cancer.

Shipeng ChenMengna LiChangning XueXiangting ZhouJianxia WeiLemei ZhengYumei DuanHongyu DengFaqing TangWei XiongBo XiangMing Zhou

Published in: Drug design, development and therapy (2024)

Cinobufotalin injection was confirmed to includes eight core ingredients, and they play therapeutic effects in liver cancer by blocking cell cycle-related pathways, which provides important insights for the mechanism of cinobufotalin injection antagonizing liver cancer and the development of novel small molecule anti-cancer drugs.

Keyphrases

cell cycle
small molecule
ultrasound guided
cell proliferation
protein protein
drug induced