Integrative omics analyses broaden treatment targets in human cancer.

Sohini SenguptaSam Q SunKuan-Lin HuangClara OhMatthew H BaileyRajees VargheseMatthew A WyczalkowskiJie NingPiyush TripathiJoshua F McMichaelKimberly J JohnsonCyriac KandothJohn WelchCynthia MaMichael C WendlSamuel H PayneDavid FenyöReid R TownsendJohn F DipersioFeng ChenLi Ding

Published in: Genome medicine (2018)

Our results suggest that an integrated analysis platform can nominate multi-omics alterations as biomarkers of druggability and aid ongoing efforts to bring precision oncology to patients.

Keyphrases

endothelial cells
end stage renal disease
single cell
newly diagnosed
ejection fraction
squamous cell carcinoma
quality improvement
patient reported outcomes
squamous cell
combination therapy
network analysis
smoking cessation