Circulating mRNA in Maternal Plasma at the Second Trimester of Pregnancy: A Possible Screening Tool for Cardiac Conotruncal and Left Ventricular Outflow Tract Abnormalities.
Elena ControLara StefaniSilvia BertoCristina LapucciDiego ArcelliDaniela PrandstrallerAntonella PeroloNicola RizzoAntonio FarinaPublished in: Molecular diagnosis & therapy (2018)
These data suggested that molecular screening of CNTRA and LVOT obstruction in the second trimester is feasible. Prospective studies are needed to test the discriminant ability of these genes and to calculate the predictive positive value in the general population.
Keyphrases
- pregnancy outcomes
- left ventricular
- preterm birth
- pregnant women
- gestational age
- birth weight
- hypertrophic cardiomyopathy
- heart failure
- cardiac resynchronization therapy
- electronic health record
- acute myocardial infarction
- genome wide
- mitral valve
- aortic stenosis
- case control
- left atrial
- big data
- binding protein
- single molecule
- bioinformatics analysis
- genome wide identification
- dna methylation
- gene expression
- weight loss
- artificial intelligence
- percutaneous coronary intervention