Palladium-Catalyzed Decarbonylative Suzuki-Miyaura Coupling of Amides To Achieve Biaryls via C-N Bond Cleavage.
Zhongfeng LuoLi XiongTingting LiuYuqi ZhangSiqi LuYuwen ChenWeijie GuoYulin ZhuZhuo ZengPublished in: The Journal of organic chemistry (2019)
The palladium-catalyzed decarbonylative Suzuki-Miyaura coupling of amides via selective amide C-N bond cleavage was reported, which afforded mild access to substitute biaryl products in the presence of low catalyst loading with NaHCO3 as the base in good yields within 4 h (29 examples).