Palladium-Catalyzed Decarbonylative Suzuki-Miyaura Coupling of Amides To Achieve Biaryls via C-N Bond Cleavage.

Zhongfeng LuoLi XiongTingting LiuYuqi ZhangSiqi LuYuwen ChenWeijie GuoYulin ZhuZhuo Zeng

Published in: The Journal of organic chemistry (2019)

The palladium-catalyzed decarbonylative Suzuki-Miyaura coupling of amides via selective amide C-N bond cleavage was reported, which afforded mild access to substitute biaryl products in the presence of low catalyst loading with NaHCO3 as the base in good yields within 4 h (29 examples).

Keyphrases

room temperature
dna binding
electron transfer
ionic liquid
transition metal
highly efficient
visible light
gold nanoparticles