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[Cell loss in retinal ischemia is associated with increased necroptosis].

Teresa TsaiLeonie DeppeH Burkhard DickStephanie Christine Joachim
Published in: Die Ophthalmologie (2024)
Necroptotic processes appear to be activated 7 days after ischemia reperfusion, contributing to retinal cell death and activation of astrocytes. Late autophagic processes are not activated 7 days after ischemia. Necroptosis-associated parameters could therefore be targeted as an early therapeutic approach after ischemia in the future.
Keyphrases
  • cell death
  • optical coherence tomography
  • diabetic retinopathy
  • single cell
  • optic nerve
  • cell cycle arrest
  • cancer therapy
  • current status
  • stem cells
  • mesenchymal stem cells
  • drug delivery