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Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8.

Takeshi TsusakaMasaki KikuchiTadahiro ShimazuTakehiro SuzukiYoshihiro SohtomeMai AkakabeMikiko SodeokaNaoshi DohmaeTakashi UmeharaYoichi Shinkai
Published in: Epigenetics & chromatin (2018)
Our findings provide new insights into the roles of lysine methylation in non-histone substrates which are targeted by the G9a/GLP complex and suggest a potential function of ATF7IP methylation in SETDB1/MPP8-mediated transgene silencing.
Keyphrases
  • dna methylation
  • genome wide
  • transcription factor
  • endoplasmic reticulum stress
  • cancer therapy
  • small molecule
  • risk assessment
  • human health
  • climate change