Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8.
Takeshi TsusakaMasaki KikuchiTadahiro ShimazuTakehiro SuzukiYoshihiro SohtomeMai AkakabeMikiko SodeokaNaoshi DohmaeTakashi UmeharaYoichi ShinkaiPublished in: Epigenetics & chromatin (2018)
Our findings provide new insights into the roles of lysine methylation in non-histone substrates which are targeted by the G9a/GLP complex and suggest a potential function of ATF7IP methylation in SETDB1/MPP8-mediated transgene silencing.