Clinical significance of CCN2/connective tissue growth factor in Behçet's disease patients.
Iman Hamed BassyouniWafaa Hob Sharkawy MohammedFatma M TahaRasha M El RefaiPublished in: International journal of rheumatic diseases (2019)
Behçet's disease patients showed a significant increase of CCN2 levels, especially in the group of patients with major organ involvement. A significant reduction of these levels was found in patients who received steroids or cyclophosphamide. Larger studies with further investigations of the precise role of CCN2 in BD pathogenesis might lead to novel therapies for the clinical management of this disease.