Sex-specific programming effects of parental obesity in pre-implantation embryonic development.

Kathrin HedeggerJulia Philippou-MassierStefan KrebsHelmut BlumStefan KunzelmannKlaus FörstemannMartina GimpflAdelbert A RoscherRegina EnsenauerEckhard WolfMaik Dahlhoff

Published in: International journal of obesity (2005) (2019)

Our study indicates that sex-specific programming effects of parental obesity already start in the pre-implantation period and reveals specific alterations of the sperm miRNA profile as mechanistic link to programming effects of paternal obesity.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
skeletal muscle
physical activity