Rapidly maturing fentanyl clearance in preterm neonates.

Swantje VöllerRobert B FlintPeter AndriessenKarel AllegaertLuc J I ZimmermannKian D LiemBirgit C P KochSinno H P SimonsCatherijne A J Knibbenull null

Published in: Archives of disease in childhood. Fetal and neonatal edition (2019)

Because of low clearance, bodyweight-based dosages may result in fentanyl accumulation in neonates with the lowest postnatal and gestational ages which may require dose reduction. Together with additional information on the pharmacodynamics, the results of this study can be used to guide dosing.

Keyphrases

low birth weight
preterm infants
weight gain
pregnant women
preterm birth
health information
gestational age
body mass index
birth weight