Characterization of tenascin-C as a novel biomarker for asthma: utility of tenascin-C in combination with periostin or immunoglobulin E.
Mina YasudaNorihiro HaradaSonoko HaradaAyako IshimoriYoko KatsuraYukinari ItoigawaKei MatsunoFumihiko MakinoJun ItoJunya OnoKazunori TobinoHisaya AkibaRyo AtsutaKenji IzuharaKazuhisa TakahashiPublished in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2018)
To our knowledge, this is the first study to show that serum TNC levels in asthmatic patients are associated with clinical features of asthma and that the combination of serum TNC and periostin levels or combination of serum TNC and total IgE levels were more useful for asthma than each single marker, suggesting that serum TNC can serve as a novel biomarker for asthma.