Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis.
Randall A OwSteven ShottsVenkata KakarlapudiJohn McIntyreRobert M NaclerioChangcheng YouAlexander PappasLindsay BraytonYina KuangJames ShaoPublished in: American journal of rhinology & allergy (2022)
LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.