Desloratadine and depression, a drug safety signal based on worldwide spontaneous reporting of side effects.

Jeltje BoerEllen EderveenBirgitta Grundmark

Published in: Upsala journal of medical sciences (2018)

We hypothesize that desloratadine may enter the CNS and that it hence in rare cases may cause a clinically relevant state of depression, a relation that patients and their treating physicians should be made aware of.

Keyphrases

end stage renal disease
depressive symptoms
ejection fraction
chronic kidney disease
newly diagnosed
primary care
sleep quality
prognostic factors
blood brain barrier
emergency department
patient reported outcomes
physical activity
drug induced