Improving standardization and accuracy of in vivo omega plot exchange parameter determination using rotating-frame model-based fitting of quasi-steady-state Z-spectra.

Julius Juhyun Chung Hahnsung Kim Yang JiDongshuang LuIris Yuwen Zhou Phillip Zhe Sun

Published in: Magnetic resonance in medicine (2024)

The model-based fitting of QUASS CEST Z-spectra enables consistent and accurate quantification of exchange parameters through Ω-plot construction by reducing error due to signal overlap and nonequilibrium CEST effects.

Keyphrases

density functional theory
high resolution
solid phase extraction
molecularly imprinted
molecular dynamics
liquid chromatography
tandem mass spectrometry