Novel Advanced Impedance Metrics on Impedance-pH Testing Predict Lung Function Decline in Idiopathic Pulmonary Fibrosis.

Vikram RanganLawrence F BorgesWai-Kit LoSravanya GaviniMariel BaileyKelly E HathornHilary J GoldbergWalter Wai-Yip Chan

Published in: The American journal of gastroenterology (2022)

Low distal MNBI, proximal MNBI, and PSPW index independently predicted more severe lung function decline over 1 year in patients with IPF. These impedance metrics may have prognostic value and support a role for reflux in IPF pathogenesis.

Keyphrases

lung function
idiopathic pulmonary fibrosis
cystic fibrosis
chronic obstructive pulmonary disease
air pollution
interstitial lung disease
dual energy
minimally invasive
computed tomography
magnetic resonance
magnetic resonance imaging
drug induced
contrast enhanced