OBESITY AND SEVERE STEATOSIS: THE IMPORTANCE OF BIOCHEMICAL EXAMS AND SCORES.
Miller Barreto de Brito E SilvaFrancisco TustumiAnna Carolina Batista DantasBarbara Cristina Jardim MirandaDenis PajeckiRoberto de ClevaMarco Aurélio SantoSergio Carlos NahasPublished in: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery (2022)
NAFLDS, FIB-4, AST/ALT, and HSI have no utility for the evaluation of severe steatosis in severely obese patients. Diabetes and insulin-resistance-related biochemical assessments, such as HOMA-IR, can be used as good screening tools for severe steatosis in these patients. APRI score is the most specific biochemical diagnostic tool for steatosis in severely obese patients and can help clinicians to decide the need for bariatric or metabolic surgery.
Keyphrases
- insulin resistance
- obese patients
- bariatric surgery
- high fat diet induced
- roux en y gastric bypass
- gastric bypass
- high fat diet
- type diabetes
- adipose tissue
- weight loss
- metabolic syndrome
- skeletal muscle
- polycystic ovary syndrome
- early onset
- glycemic control
- end stage renal disease
- ejection fraction
- minimally invasive
- newly diagnosed
- prognostic factors
- palliative care
- peritoneal dialysis
- cardiovascular disease
- chronic kidney disease
- body mass index
- coronary artery bypass
- physical activity
- atrial fibrillation