A separable nanodevice enables multilayer imaging of diverse biomarkers for precise diagnosis.
Sha YuYao SunJingyi CaiYuanzhen ZhouJun-Jie ZhuPublished in: Chemical communications (Cambridge, England) (2023)
An acid-driven separable nanodevice was designed for multilayer imaging of diverse biomarkers with different spatial distributions in living cells. The proposed nanodevice can simultaneously perform in situ imaging of the intracellular microRNAs and extracellular pH, affording a new approach to develop a precise imaging system for disease diagnosis.