Description of Copy Number Variations in a Series of Children and Adolescents with FASD in Reunion Island.

Laëtitia SennsfelderSusie GuillySébastien LerusteLudovic HoareauWilly LéocadiePauline BeuvainMeïssa NekaaMaïté BagardStéphanie RobinJustine LanneauxLéa EtchebarrenMarilyn TallotMichel SpodenkiewiczJean-Luc AlessandriGodelieve MorelMaud BlanluetPaul GueguenBérénice Roy-Doray

Published in: Children (Basel, Switzerland) (2023)

A particularly high number of CNVs was found in children and adolescents with FASD. It reinforces the plea for a multidisciplinary approach for developmental disorders to explore both environmental factors, such as avoidable teratogens and intrinsic vulnerabilities, especially genetic determinants.

Keyphrases

copy number
spectrum disorder
mitochondrial dna
genome wide
dna methylation
quality improvement
gene expression