Acute Kidney Injury, Systemic Inflammation and Long-term Cognitive Function: ASSESS-AKI.
Pavan K BhatrajuLeila R ZelnickIan B StanawayTalat Alp IkizlerSteven MenezVernon M ChinchilliSteve G CocaJames S KaufmanPaul L KimmelChirag R ParikhAlan S GoEdward D SiewMark M WurfelJonathan HimmelfarbPublished in: Clinical journal of the American Society of Nephrology : CJASN (2024)
AKI was associated with lower 3MS scores and sTNFR-1 concentrations appeared to mediate a significant proportion of the risk of long-term cognitive impairment. Further work is needed to determine if AKI is causal or a marker for cognitive impairment.