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Gastroprotective Effect of Azilsartan Through Ameliorating Oxidative Stress, Inflammation, and Restoring Hydroxyproline, and Gastrin Levels in Ethanol-Induced Gastric Ulcer.

Renas Raouf Hama AminTavga Ahmed Aziz
Published in: Journal of inflammation research (2022)
The study revealed that azilsartan possesses a gastroprotective effect. The proposed mechanisms could be increased blood flow to the stomach, antioxidant capacity, and anti-inflammatory activity along with restoring hydroxyproline and gastrin levels. These findings suggest azilsartan as a promising candidate to be tested in a clinical setting.
Keyphrases
  • blood flow
  • oxidative stress
  • diabetic rats
  • dna damage
  • high glucose
  • ischemia reperfusion injury
  • induced apoptosis
  • single cell
  • drug induced
  • endothelial cells
  • signaling pathway