Chronic persistent surgical pain is strongly associated with COMT alleles in patients undergoing cardiac surgery with median sternotomy.

Goduguchintha DharaniprasadAloka SamantarayLokanathan SrikanthMangu Hanumantha RaoAbha ChandraPotukuchi Venktata Gurunadha Krishna Sarma

Published in: General thoracic and cardiovascular surgery (2020)

The dominant effect of mutant COMT alleles connecting with low enzyme activity resulted in CPSP, warrants COMT genetic analysis prior to surgery was useful to predict the occurrence of CPSP.

Keyphrases

cardiac surgery
patients undergoing
minimally invasive
chronic pain
acute kidney injury
risk assessment
coronary artery bypass
pain management
neuropathic pain
surgical site infection
heart failure
spinal cord injury
spinal cord
left ventricular
atrial fibrillation
coronary artery disease