Brain mGlu5 Is Linked to Cognition and Cigarette Smoking but Does Not Differ From Control in Early Abstinence From Chronic Methamphetamine Use.
Megan N McClintickRobert M KesslerMark A MandelkernTarannom MahmoudieDaicia C AllenHilary LachoffJean-Baptiste F PochonDara G GhahremaniJudah B FarahiEdwin PartiaiRobert A CasillasLarissa J MooneyAndy C DeanEdythe D LondonPublished in: The international journal of neuropsychopharmacology (2024)
Abstinent MUD patients show no evidence of mGlu5 downregulation in brain, but association of VT in dorsolateral prefrontal cortex with verbal learning suggests that medications that target mGlu5 may improve cognitive performance.
Keyphrases
- prefrontal cortex
- white matter
- end stage renal disease
- working memory
- ejection fraction
- newly diagnosed
- resting state
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- cell proliferation
- cerebral ischemia
- signaling pathway
- multiple sclerosis
- transcranial magnetic stimulation
- patient reported outcomes
- transcranial direct current stimulation
- subarachnoid hemorrhage
- high frequency