Immunohistochemical assessment of the diagnostic utility of PD-L1: a preliminary analysis of anti-PD-L1 antibody (SP142) for lymphoproliferative diseases with tumour and non-malignant Hodgkin-Reed-Sternberg (HRS)-like cells.

Ayako SakakibaraKei KohnoAhmed E EladlTeerada KlaisuwanEri IshikawaYuka SuzukiSatoko ShimadaMasato NakaguroYoshie ShimoyamaTaishi TakaharaSeiichi KatoNaoko AsanoShigeo NakamuraAkira Satou

Published in: Histopathology (2018)

Immunohistochemical evaluation of PD-L1 expression in tumour and non-malignant HRS-like large cells may be useful for assessing either immune escape or immunodeficiency in their pathogenesis.

Keyphrases

induced apoptosis
cell cycle arrest
epstein barr virus
hodgkin lymphoma
cell death
endoplasmic reticulum stress
signaling pathway
pi k akt