RUNX2 mutation inhibits the cellular senescence of dental follicle cells via ERK signalling pathway.

LingLi JiJie LiDandan LiuYanchun QiaoWeiwei ZhaoYang Liu Shu Guo Zheng

Published in: Oral diseases (2023)

RUNX2 mutation delayed DFCs senescence through the ERK signalling pathway, which may be responsible for delayed permanent tooth eruption in CCD patients.

Keyphrases

signaling pathway
end stage renal disease
induced apoptosis
transcription factor
dna damage
ejection fraction
cell proliferation
chronic kidney disease
endothelial cells
pi k akt
newly diagnosed
prognostic factors
cell cycle arrest
stress induced
oxidative stress