Pharmacodynamic Studies of Fluorescent Diamond Carriers of Doxorubicin in Liver Cancer Cells and Colorectal Cancer Organoids.

Ron FiresteinCezary MarcinkiewiczLinyan NieHui Kheng ChuaInes Velazquez QuesadaMarco TorelliMark SternbergBojana GligorijevicOlga ShenderovaRomana SchirhaglGiora Z Feuerstein

Published in: Nanotechnology, science and applications (2021)

The rapid uptake and profound cancer inhibition observed using FDP-DOX in clinically relevant cancer models, highlight FDP-DOX promise for cancer chemotherapeutics. We also conclude that the in vitro data justify further investment in in vivo POC studies.

Keyphrases

papillary thyroid
squamous cell
lymph node metastasis
big data
squamous cell carcinoma
young adults
machine learning
quantum dots
childhood cancer
cell death
cell proliferation
oxidative stress
case control
living cells
loop mediated isothermal amplification
sensitive detection
fluorescent probe