Predictive value of retinal atrophy for cognitive decline across disease duration in multiple sclerosis.
Salut Alba-ArbalatElisabeth SolanaElisabet Lopez-SoleyAnna Camos-CarrerasEloy Martinez-HerasFrancesc VivóIrene Pulido-ValdeolivasMagi AndorraMaria SepulvedaJose María CabreraElianet FonsecaAlberto CalviRafel AlcubierreMarina Dotti-BoadaAlbert SaizElena Hernandez Martinez-LapiscinaPablo VillosladaYolanda BlancoBernardo Sanchez-DalmauSara LlufriuPublished in: Journal of neurology, neurosurgery, and psychiatry (2023)
The progressive retinal thinning is related to cognitive decline, indicating that cognitive dysfunction is a late manifestation of accumulated neuroaxonal damage. Quantifying the pRFNL aids in identifying individuals at risk of cognitive dysfunction.