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Plasma soluble leptin receptor levels are associated with pancreatic β-cell dysfunction in patients with type 2 diabetes.

Tomoaki MoriokaMasanori EmotoYuko YamazakiMasafumi KurajohKoka MotoyamaKatsuhito MoriShinya FukumotoAtsushi ShioiTetsuo ShojiMasaaki Inaba
Published in: Journal of diabetes investigation (2017)
Plasma soluble Ob-R levels are independently associated with pancreatic β-cell function, but not with insulin resistance, in patients with type 2 diabetes. The present study implicates the role of soluble Ob-R in pancreatic β-cell dysfunction in type 2 diabetes.
Keyphrases
  • type diabetes
  • insulin resistance
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  • cell therapy
  • oxidative stress
  • cardiovascular disease
  • skeletal muscle
  • high fat diet
  • glycemic control
  • mesenchymal stem cells