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Send it, receive it, quick erase it: A mouse model to decipher chemokine communication.

Leen HermansTimothy E O'Sullivan
Published in: The Journal of experimental medicine (2024)
A method to precisely determine which cells respond to chemokines in vivo is currently lacking. A novel class of dual fluorescence reporter mice could help identify cells that produce and/or sense a given chemokine in vitro and in vivo (Rodrigo et al. 2024. J. Exp. Med.https://doi.org/10.1084/jem.20231814).
Keyphrases
  • induced apoptosis
  • mouse model
  • cell cycle arrest
  • endoplasmic reticulum stress
  • crispr cas
  • cell death
  • adipose tissue
  • single molecule
  • metabolic syndrome
  • cell proliferation
  • quantum dots
  • high fat diet induced