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Peripheral nerve regeneration following scaffold-free conduit transplant of autologous dermal fibroblasts: a non-randomised safety and feasibility trial.

Ryosuke IkeguchiTomoki AoyamaTakashi NoguchiMika UshimaruYoko AminoAkiyoshi NakakuraNoriko MatsuyamaShiori YoshidaMomoko Nagai-TanimaKeiko MatsuiYasuyuki AraiYoko ToriiYudai MiyazakiShizuka AkiedaShuichi Matsuda
Published in: Communications medicine (2024)
Bio 3D nerve conduits were successfully used for clinical nerve reconstruction without adverse events and are a possible treatment option for peripheral nerve injuries.
Keyphrases
  • peripheral nerve
  • clinical trial
  • study protocol
  • stem cells
  • open label
  • phase iii
  • bone marrow
  • phase ii
  • cell therapy
  • double blind
  • wound healing
  • extracellular matrix
  • placebo controlled
  • combination therapy