Utility of Intravenous Alteplase Prior to Endovascular Stroke Treatment: A Systematic Review and Meta-analysis of RCTs.

Aristeidis H KatsanosGuillaume TurcMarios PsychogiosJohannes KaesmacherLina PalaiodimouMaria Ioanna StefanouGeorge MagoufisAshkan ShoamaneshMarios ThemistocleousSimona SaccoFiehler JensJan GrallaDaniel StrbianAndrei V AlexandrovUrs FischerGeorgios Tsivgoulis

Published in: Neurology (2021)

We detected no differences in functional outcomes of IV thrombolysis-eligible patients with an acute LVO receiving dEVT compared to BT. Because uncertainty for most endpoints remains large and the available data are not able to exclude the possibility of overall benefit or harm, further RCTs are needed.

Keyphrases

acute ischemic stroke
liver failure
aortic dissection
pulmonary embolism
atrial fibrillation
electronic health record
respiratory failure
drug induced
deep learning
replacement therapy
subarachnoid hemorrhage