A Hybrid Model Associating Population Pharmacokinetics with Machine Learning: A Case Study with Iohexol Clearance Estimation.

Alexandre DesterePierre MarquetCharlotte Salmon GandonnièreAnders ÅsbergVéronique Loustaud-RattiPaul CarrierStephan EhrmannChantal Barin-Le GuellecAurélie PremaudJean Baptiste Woillard

Published in: Clinical pharmacokinetics (2022)

In conclusion, this hybrid algorithm represents a significant improvement in comparison to MAP-BE estimation alone.

Keyphrases

machine learning
deep learning
artificial intelligence
big data