Nifuroxazide ameliorates pulmonary fibrosis by blocking myofibroblast genesis: a drug repurposing study.

Cailing GanQianyu ZhangHongyao LiuGuan WangLiqun WangYali LiZui TanWenya YinYuqin YaoYongmei XieLiang OuyangLuoting YuTinghong Ye

Published in: Respiratory research (2022)

Taken together, we conclude that NIF inhibits and reverses pulmonary fibrosis, and these results support NIF as a viable therapeutic option for IPF treatment.

Keyphrases

pulmonary fibrosis
idiopathic pulmonary fibrosis
mouse model
emergency department
combination therapy
epithelial mesenchymal transition
drug induced
transforming growth factor
smoking cessation