Pattern of bleeding in a large prospective cohort of haemophilia A patients: A three-year follow-up of the AHEAD (Advate in HaEmophilia A outcome Database) study.

Kate KhairM G MazzucconiR ParraE SantagostinoD A TsakirisC HermansJohannes OldenburgG SpottsK Steinitz-TrostA Gringeri

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2017)

These data confirm that the goal of zero bleeds is achievable, although not yet achieved in all patients. Understanding reasons behind the lower response to standard prophylaxis regimens in some patients and personalizing prophylactic treatment may further improve outcome in patients with haemophilia A.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
emergency department
machine learning
big data