HPV and DNA Methylation Testing in Urine for Cervical Intraepithelial Neoplasia and Cervical Cancer Detection.

Rianne van den Helder Renske D M SteenbergenAnnina P van SplunterConstantijne H MomMing Y TjiongIvonne MartinFleur M F Rosier-van DunnéIrene A M van der AvoortMaaike C G BleekerNienke E van Trommel

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

HrHPV DNA and DNA methylation testing in urine offers a promising solution to detect cervical cancer and CIN2/3 lesions, especially for women currently unreached by conventional screening methods.

Keyphrases

dna methylation
high grade
genome wide
gene expression
cervical cancer screening
polycystic ovary syndrome
circulating tumor
single molecule
copy number
cell free
pregnancy outcomes
label free
metabolic syndrome
nucleic acid
quantum dots